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Diagnosticul de mononucleoză infecţioasă se stabileşte pe date clinice (febră, faringită, adenopatii, hepatosplenomegalie), aspectul frotiului de sânge periferic (limfomonocite。

Anticorpi anti-antigenul precoce (Anti-EA, Early Antigen) Anticorpi anti-antigenul nuclear EBV (EBNA, EBV Nuclear Antigen) CDC nu mai recomanda folosirea in practica。

The mononuclear spot test or monospot test, a form of the heterophile antibody test, is a rapid test for infanticorpi heterofiliectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. The test is specific for heterophile antibodies produced by the human immune system in response to EBV infection. Commercially available test kits are 70–92% sensitive and 96–100% specific, wi…

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